An index that estimates insulin resistance from fasting glucose and fasting insulin.

Why it matters for PCOS

HOMA-IR is worked out from fasting glucose and fasting insulin, giving a single figure that estimates the degree of insulin resistance without complex testing. Insulin resistance is common in PCOS and can contribute to irregular cycles and androgen-related signs, so the value is sometimes used to gauge metabolic risk. That said, HOMA-IR is not used widely in routine PCOS diagnosis and is not part of the diagnostic criteria.

A high HOMA-IR suggests possible insulin resistance, while a low value suggests better insulin sensitivity. The number should be read alongside your glucose, HbA1c, and overall clinical picture rather than on its own, and reference ranges differ between laboratories.

This glossary is education, not diagnosis. For your own situation, ask a doctor or pharmacist.